Compounds in cluster

There are 10 purchasable compounds for target: Serine protease 1/Trypsin-2

Wt: 214.2 BDBM50027795 Purchase	Wt: 521.6 BDBM50037996 Purchase	Wt: 256.2 BDBM50087944 Purchase	Wt: 217.2 BDBM50087989 Purchase	Wt: 205.2 BDBM50087992 Purchase
Wt: 213.2 BDBM50087996 Purchase	Wt: 278.1 BDBM50087910 Purchase	Wt: 229.2 BDBM50087914 Purchase	Wt: 213.2 BDBM50087927 Purchase	Wt: 471.5 BDBM50112086 Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50027795,50037996,50087944,50087989,50087992,50087996,50087910,50087914,50087927,50112086
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50112086 (3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	50.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma KG Curated by ChEMBL					Assay Description Inhibitory constant (Ki) was determined against human trypsin				J Med Chem 45: 1757-66 (2002) BindingDB Entry DOI: 10.7270/Q2GX49W5
Boehringer Ingelheim Pharma KG Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50037996 (1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50087944 (CHEMBL53801 \| N-[4-(Diaminomethylene-sulfamoyl)-ph...) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NC(N)=N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50087989 (CHEMBL53755 \| N-Diaminomethylene-4-fluoro-benzenes...) Show SMILES NC(=N)NS(=O)(=O)c1ccc(F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50087910 (4-Bromo-N-diaminomethylene-benzenesulfonamide \| CH...) Show SMILES NC(=N)NS(=O)(=O)c1ccc(Br)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50087914 (CHEMBL51103 \| N-Diaminomethylene-4-methoxy-benzene...) Show SMILES COc1ccc(cc1)S(=O)(=O)NC(N)=N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50087992 (CHEMBL51261 \| Thiophene-2-sulfonic acid diaminomet...) Show SMILES NC(=N)NS(=O)(=O)c1cccs1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50087996 (CHEMBL53543 \| N-Diaminomethylene-C-phenyl-methanes...) Show SMILES NC(=N)NS(=O)(=O)Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50027795 (1N-amino(imino)methyl-4-amino-1-benzenesulfonamide...) Show SMILES NC(=N)NS(=O)(=O)c1ccc(N)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50087927 (CHEMBL50185 \| N-Diaminomethylene-4-methyl-benzenes...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(N)=N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human trypsin (using Chromozym TH as the substrate)				J Med Chem 43: 1793-806 (2000) BindingDB Entry DOI: 10.7270/Q2NZ88B0
Universit£ degli Studi Curated by ChEMBL					More data for this Ligand-Target Pair